Failure to suppress testosterone in Oestragen therapy (UK)

• Posted by Hannah Ceridwen Eluned Cavendish-Grosvenor August 2, 2016 Filed in Society Girl's Personal Blogs 1,250 views
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  FINAL PART:

   

  After an appropriate period of Oestragen therapy, the levels achieved are within the satisfactory female 400 to 600. However, in some cases  there is a failure in testosterone suppression and its levels remail refractory, in the male range.

   

  TREATMENT MODIFICATION:

   

  Additional therapy is in the form of Decapeptyl 11.25 mgs every 12 weeks as an addition to current therapy, in order to suppress the testosterone production.

  For the initial 2 weeks following injection No 1, the physician will co-administer Cyproterone acetate 100 mgs once daily, to suppress the flare in testosterone that can occur with initiation of GnRH analogues.

  This is not required after subsequent injections.

   

  TESTS:

   

  * weeks after commencement of the above additional therapy, blood should be drawn for oestradiol, testosterone, prolactin, SHBG and Liver Function..