Superfemale (XX+X): Triple X Syndrome

• Posted by Hannah Ceridwen Eluned Cavendish-Grosvenor October 23, 2016 1,484 views
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  It is unfortunate that the early researchers tried to popularise their work, and presumably themselves, with this title ( Patricia A Jacobs et al in Edinburgh, 1959 and several articles in the Lancet: 2 January 1960 and 17 September)

   

  Bernard Lennox, Principal advisor on medical terms to the Oxford English Dictionary chose to publish this erronious and misleading word to describe XXX females.

   

  Triple X Syndrome occurs in 1 in 1000 girls.

  It is NOT inherited.

  The majority are never diagnosed.

  Some have XX cells and XXX cells. This is called a mosaic.

  Observable physical anomalies: rare except for 'taller than average and sisters'.

  So few XXX females are identified that effects are not easily identified and samples may not be significant: characteristics may include:-

  No effects or extremely mild

  Stature - tall (accelerated growth to puberty), small head, epicanthic (eyelid) folds, speech learning difficulties (dyslexia)

  Potential risks:-

  Auditory processing disorders, delayed language development, motor co-ordination problems, scoliosis

  Poor school academic performance, psychological and personality problems

  Early ovarian failure, despite normal fertility

  Anxiety, shyness and low self-esteem

  Benificial aids:

  Stable and happy home environment

  Leaving school

   

  Physical tests:

  blood test confirms XXX, EEG abnormalities