November 19, 2008 11:26 AM GMT
October 26, 2008 5:09 PM GMT
There’s no reason why you shouldn’t take estradiol valerate sublingually (unless your brand tastes disgusting, but I don’t think Progynova does).
Estrofem has very low hepatic toxicity, it’s extremely safe in low doses. Estradiol valerate is the next best thing, in fact it’s virtually identical and probably equally safe to use. If I was getting good results on 2mg valerate I’d stick to that, but by all means give the Estrofem a go, starting on the same dose. I cant really see any advantage though.
I don’t know how much estradiol is actually absorbed straight into the blood stream when taken sublingually, but I always take that way in the hope that less is removed by the liver (first pass effect). The longer the tablet spends in your mouth, the better; you don’t want it to dissolve.
Provera - I would avoid like the plague, it’s not progesterone, it is a progestin. I’m not being pedantic, there is a big difference in effects between the two and a whole host of common side effects associated with Provera. Switch to Micronised progesterone, ie bio-identical to human progesterone: Microgest, Prometrium, Cyclogest, or Utrogestan.
xx
November 20, 2008 3:37 PM GMT
Hi Amber, I have been away for a a couple of weeks, so haven’t been intentionally ignoring you! You’ve no reason to apologise, and I will answer your messages when I have more time.
A progestin is a synthetic version of progesterone. They are commonly prescribed to women in this country on HRT, evidence suggests that it helps to prevent endometrial cancer which can be a possible risk from the use of estrogen alone (“unopposed estrogen”). Progestins however do not have the same beneficial effects for M2F TS’s as progesterone, in fact they can have an adverse effect on feminisation (unlike progesterone). Since we don’t have an endometrium (lining of the uterus) we simply shouldn’t take it. Doctors who prescribe it to us are I’m afraid just being ignorant.
I don’t think it will do you ant real harm taking it for a short time, but it’s unlikely to do you any good either. Micronised progesterone is what you want.
xx