i am 40 yr male, i have taken premarine 0.625mg and progynova 2mg , 2 time daily for 2 month. as i want to be M2F.  and by such medicine hardness of my tool is completely lost. now  i have stopped taken such medicine from last 2 weeks. i want to be again in my previous normal life and live like male, but still i am not geting any hardness in my tool. please tell me, can the effect of such medicine get reverse or any other way by which i can return to my previous life.

Anil,

You need to be patient, not all function is lost from estrogen use. 

In fact, not all function is lost after orchidectomy (removal of the testes).

If you are in a hurry you could use Viagara or change over to testosterone medications. 

I've had testosteroe injections and they work fine.

Your problems are more likely to be due to stress or anxiety.

how much time it will take to return back at original condition. for how much duration the effect of medicine remain in body? effect of using testosterone medicine is parmanent or temporary? by using testosterone medicine will i return back to my original condition?

You should see a Doctor as every individual is different.

If I was to change back to non-transitioning, I would start with lots of rest, diet and exercise.   

Anil - you are in a BAD place. For goodness sake, talk to you Doctor, or better  still, a specialist endocrinologist AS SOON AS POSSIBLE.  Irreversible effects are unlikely at this stage.  The psychiatric bit can come later if it is necessary.

Amanda Bruce, MNRHP, ADHP, DEH(NC), ECP, UKCP Reg.

Site Psychotherapist