Hello I have a quick question has anyone hear heard of it making a significant difference injectioning into the thigh vs the glute region. I have been on IM estradiol since January 2017 and the progress has been slow going. For the majority of the time I have been injecting into my thigh area. Here recently I decided to change to my hip area to see if that would make a difference. What I believe was happening is my body is burning off the shot in the thigh too quickly and the levels drop precipitously before it has had a chance to do its magic. The last time I had some blood work done was back in early april in my estradiol was off the charts at 1800+pg/mL I am going back to her in July to discuss this with her but I just wanted to get some differing idea and to see if anyone else has gone through anyting similar.